IITRI to Post Research Findings at SOT Meeting

IITRI scientists will share their recent research findings in several presentation posters at the 44th annual meeting of the Society of Toxicology (SOT) March 6-10, 2005, in New Orleans, LA. They will present the following abstracts:

• "Subchronic Oral Toxicity of the Corticotropin-Releasing Hormone (CRH) Receptor Antagonist, Antalarmin, in Dogs." William D. Johnson, J. Brooks Harder and David L. McCormick, IITRI; Robert L. Morrissey, Pathology Associates, Chicago, IL; Karim Calis, Philip W. Gold, Giovanni Cizza, Dennis Charney, Elizabeth R. Glaze and Joseph E. Tomaszewski, National Institutes of Health, Bethesda, MD.


• "Genetic Toxicology and Bone Marrow Cytotoxicity Studies of the Corticotropin-Releasing Hormone (CRH) Receptor Antagonist, Antalarmin." Patrick T. Curry, Moolky Nagabhushan and David L. McCormick, IITRI; Ralph E. Parchment, SciTech Development LLC, Grosse Pointe, MI; Karim Calis, Philip W. Gold, Giovanni Cizza, Dennis Charney, Elizabeth R. Glaze and Joseph E. Tomaszewski, National Institutes of Health, Bethesda, MD.


• "Subchronic Oral Toxicity of the Corticotropin-Releasing Hormone (CRH) Receptor Antagonist, Antalarmin, in Rats." Thomas L. Horn, William D. Johnson and David L. McCormick, IITRI; Robert L. Morrissey, Pathology Associates, Chicago, IL; Karim Calis, Philip W. Gold, Giovanni Cizza, Dennis Charney, Elizabeth R. Glaze and Joseph E. Tomaszewski, National Institutes of Health, Bethesda, MD.


• "Focal Proliferative Lesions in A/J Mouse Lung Following 5-Month Exposure to Mainstream Cigarette Smoke." Jonathan Hamm and Simon Yee, Lorillard Tobacco Co., Greensboro, N.C.; Narayanan Rajendran, IITRI; Robert L. Morrissey, Pathology Associates, Chicago, IL; Manoj Misra, Lorillard Tobacco Co.


• "Toxicological Evaluation of a Cigarette Paper with Reduced Ignition Propensity: in vitro and in vivo Tests." Manoj Misra, Robert D. Leverette, Jonathan T. Hamm, Melanee B. Bennett and J. Daniel Heck, Lorillard Tobacco Co., Greensboro, NC; Robert L. Morrissey, Pathology Associates, Chicago, IL; Narayanan Rajendran, IITRI.


• "Effects of Particle Size on the Systemic Bioavilability in Rats Following Inhalation Exposure." Shu C. Hu, IITRI; Bruce D. Naumann, Merck & Co., Inc., Whitehouse Station, NJ; Michael J. Cwik and Narayanan Rajendran, IITRI.

The SOT annual meeting is the largest toxicology meeting and exhibition in the world, attracting approximately 6,000 scientists from industry, academia and government. The program includes a plenary and other special lectures, symposia, workshops, roundtable discussions, and platform and poster presentations. Continuing education courses will be offered, and SOT annual awards will be presented.