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    Toxicology

    IITRI has designed and conducted a broad range of IND Enabling and safety programs, from acute through chronic, and carcinogenicity studies.

    Areas of expertise include:

    Acute Toxicity - (Limit Tests, LD50s, LC50s, RD50s, MTD, Irritation)

    Developmental and Reproductive Toxicology

    Subchronic Toxicology

    Carcinogenicity Bioassays

    Chronic Toxicology

    Immunotoxicology

    Toxicokinetics

    Neurotoxicology

    Pharmacokinetics

    Vaccine Toxicology


    Routes of Exposure:

    Oral (Gavage, Feed, Water)

    Infusion (continuous or intermittent)

    Ocular

    Inhalation

    Dermal

    Intratracheal

    Intraperitoneal

    Intranasal

    Intravenous

    Subcutaneous

    Intramuscular

    Etc.


    Animal Models:

    Rodent and Rabbits

    Canine

    Non-Human Primates (NHP)